Search on: TRYPTOPHAN HYDROXYLASE 
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Descriptor English:   Tryptophan Hydroxylase 
Descriptor Spanish:   Triptófano Hidroxilasa 
Descriptor Portuguese:   Triptofano Hidroxilase 
Synonyms English:   Hydroxylase, Tryptophan
Monooxygenase, Tryptophan
Tryptophan Monooxygenase  
Tree Number:   D08.811.682.690.708.870
Definition English:   An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN. 
See Related English:   Tryptophan Oxygenase
 
History Note English:   78(73); was see under HYDROXYLASES 1975-77 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   14767 
Unique Identifier:   D014365 

Occurrence in VHL:
 

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